- Energy Release
- Liver-Protective
What is it?
D-Glucurono-γ-lactone, or in organic chemistry
nomenclature, D-glucurono-3,6-lactone (henceforth referred to as DGL)
is a natural metabolite of glucose and regulates the formation of
glycogen. Its precursor, D-glucuronic acid (henceforth referred to as
DGA) remains in an equilibrium state with glucuronolactone at
physiological pH.
Is it
Liver-Protective?
DGL is most likely hepatoprotective, meaning it will reduce
ill effect or even improve the physical state and function of the
liver. In a Chinese research study using an herbal concoction called
gan-xian-fang, of which DGL is a component, they measured a marked
improvement in patients with hepatic fibrosis resulted from hepatitis B4.
This study was a double-blind controlled trial funded by the
Chinese Ministry of Public Health and published in the Chinese Medical
Journal giving scientifically valid results. This research is not
conclusive, given that DGL is not isolated for its actions, but it does
reinforce of potential benefits and safety.
How is
it used ??
Supplementing with 1-3 grams of DGL in its pure, powder form,
typically report positive results in terms of perceived energy and
alertness. This would be the dosage I would recommend to the athlete
desiring to supplement with DGL. This dosing is predicated on the
safety data foremost, which is considerable.
It should be noted that Red Bull® has 600 mg. of DGL, but also
has other substances that may work in additive or synergistic fashion
(e.g. caffeine, taurine, B-vitamins) that may necessitate a lower dose
to yield the desired effects.